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Since storage additives are devoid of amino acids, elevation in intracellular amino acids is consistent with proteolysis (e.g., via proteasomal degradation), a phenomenon that is mechanistically linked to (extravascular) hemolysis 45
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Chen YC, Chiu WC, Cheng TT et al (2017) Delayed anti-TNF therapy increases the risk of total knee replacement in patients with severe rheumatoid arthritis
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